- South Texas International at Edinburg AirportIdent: KEBGServes: Edinburg
- South Texas Regional Airport at HondoIdent: KHDOServes: Hondo
- South Trap AirportIdent: US-8953Serves: Christoval
- Southard FieldIdent: O55Serves: Bieber
- Southbridge Municipal AirportIdent: K3B0Serves: Southbridge
- Southeastern AirportIdent: FD30Serves: Fort Pierce
- Southerland StripIdent: FD92Serves: Geneva
- Southerly AirportIdent: 58FDServes: Dundee
- Southern Agricultural Aviation AirportIdent: 1GA4Serves: Statesboro
- Southern California Logistics AirportIdent: KVCVServes: Victorville
- Southern Comforts AerodromeIdent: 61NCServes: Parkton
- Southern Cross AirportIdent: C01Serves: Williamstown
- Southern Fruit Groves AirportIdent: FD24Serves: Port St. Lucie
- Southern Helicopters AirportIdent: 21LAServes: Baton Rouge
- Southern Oaks AirportIdent: GE35Serves: Bostwick
- Southern Seaplane AirportIdent: 65LAServes: Belle Chasse
- Southern Skies AirstripIdent: NR04Serves: Taylorsville
- Southern Wisconsin Regional AirportIdent: KJVLServes: Janesville
- Southfork AirportIdent: 81TNServes: Bristol
- Southland FieldIdent: KUXLServes: Sulphur
- Southland Flying Service AirportIdent: MS40Serves: Tchula
- Southwest Michigan Regional AirportIdent: KBEHServes: Benton Harbor
- Southwest Minnesota Regional Airport - Marshall/Ryan FieldIdent: KMMLServes: Marshall
- Southwind AirportIdent: 22WNServes: Dodgeville
- Spadaro AirportIdent: 1N2Serves: East Moriches
- Spalding AirportIdent: K1Q2Serves: Susanville
- Spangle FieldIdent: 03WAServes: Spangle
- Spanish Fork Municipal Airport/Woodhouse FieldIdent: KSPKServes: Spanish Fork
- Spanish Peaks AirfieldIdent: K4V1Serves: Walsenburg
- Spanish Springs AirportIdent: N86Serves: Reno
- Sparta Community Airport - Hunter FieldIdent: KSARServes: Sparta
- Sparta Fort McCoy AirportIdent: KCMYServes: Sparta
- Spartanburg Downtown Memorial AirportIdent: KSPAServes: Spartanburg
- Spaudling AerodromeIdent: 28NYServes: Cassadaga
- Spear Valley AirportIdent: 55IDServes: Sandpoint
- Spearman FieldIdent: 4MS4Serves: Shannon
- Spearman Municipal AirportIdent: KE42Serves: Spearman
- Spectre AirportIdent: XA07Serves: Chico
- Spence AirportIdent: KMULServes: Moultrie
- Spencer AirportIdent: 60MServes: Spencer
- Spencer AirportIdent: VT09Serves: Addison
- Spencer FieldIdent: 2MS8Serves: Grenada
- Spencer FieldIdent: 7NC9Serves: Asheboro
- Spencer FieldIdent: MU73Serves: Highlandville
- Spencer Municipal AirportIdent: KSPWServes: Spencer
- Spencer Nolf AirportIdent: KNRQServes: Pace
- Spencer's AirparkIdent: FL13Serves: Middleburg
- Spencerport AirparkIdent: D91Serves: Spencerport
- Spezia AirportIdent: 9CL9Serves: Walnut Grove
- Spickard Farm AirportIdent: 5CO4Serves: Byers
- Spiegel FieldIdent: WI40Serves: Oregon
- Spiering AirportIdent: 8MD4Serves: Greensboro
- Spillers Club AirportIdent: LA76Serves: Breaux Bridge
- Spirit AirparkIdent: DE20Serves: Townsend
- Spirit Lake Municipal AirportIdent: US-0F3Serves: Okoboji
- Spirit of Suwannee AirportIdent: 95FAServes: Suwannee
- Spitfire AerodromeIdent: 7N7Serves: Pedricktown
- Splan AirportIdent: 2ID5Serves: McCall
- Sport Flyers AirportIdent: 27XSServes: Brookshire
- Sports Mans Paradise AirportIdent: 9AK0Serves: Tok